Now Approved

RELYVRIO™ is a new prescription oral therapy for adults living with ALS shown to help SLOW DISEASE PROGRESSION.

Rachel lives in a San Francisco art community. The former actress, production company owner, burlesque troupe founder, and current artist is one of the most resilient people you’ll ever meet. She’s always been inspired to do something different. Now she’s determined to do more.

TAKE ON ALS WITH RELYVRIO

How RELYVRIO can help

RELYVRIO is a new prescription oral therapy for adults living with ALS shown to help slow disease progression.

Why RELYVRIO

What to expect

In the CENTAUR clinical trial for RELYVRIO, the most common side effects were diarrhea, abdominal pain, nausea, and upper respiratory tract infection.

Taking RELYVRIO

Financial support programs

Resources are available for eligible individuals, including a $0 co-pay program and an interim access program for those with commercial insurance, and a program for people without insurance who cannot afford to pay.

Financial Support

Priscilla
ACT Care Coordinator

The Amylyx Care Team (ACT)™ Provides Support You Can Count On

If your doctor has decided that RELYVRIO is right for you, that’s when ACT comes in. ACT is a personalized support program designed to help meet your individual needs as you start and continue on RELYVRIO. The ACT Support Program may help with reimbursement and insurance support, financial assistance (if eligible), ALS education, and additional support.

Visit ACT Now

“I STILL HAVE MORE TO DO”

Gwen is a wife, aunt, and spoiler of a miniature goldendoodle named Annabelle. She and her husband, Nathan, share a dream to travel and a passion for good food. She’s not ready to give up any of it. So, from raising awareness to advancing public policy, she’s doing all she can to advocate for everyone living with ALS.

“HEY ALS, THIS ISN’T OVER”

Renee is a former university professor with a Doctor of Education and a Masters in Nursing Education. She’s competed as a triathlete and was an avid cyclist and swimmer. She always loves spending time with her family, especially her nieces and nephews. Renee is more than ALS. She has more to do and will continue to fight.

“You have more to do.RELYVRIO MAY help.”

Discover RELYVRIO

IMPORTANT SAFETY INFORMATION

Before you receive RELYVRIO, tell your doctor about all of your medical conditions, including if you:

Have pancreas, liver, or intestinal problems
Have heart failure, including congestive heart failure
Have high blood pressure
Have kidney problems
Are pregnant or plan to become pregnant. It is not known if RELYVRIO will harm your unborn baby
Are breastfeeding or plan to breastfeed. It is not known if RELYVRIO passes into your breast milk. You and your doctor should decide the best way to feed your baby

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements and any taurursodiol products, such as tauroursodeoxycholic acid (TUDCA).

RELYVRIO may affect the way other medicines work, and other medicines may affect how RELYVRIO works.

What are the possible side effects of RELYVRIO?

RELYVRIO may cause serious side effects, including:

Changes in bile acid levels. RELYVRIO may increase bile acid levels and cause worsening diarrhea if you already have problems with your liver, bile ducts, or pancreas. Your doctor should monitor you for these side effects. Some disorders of the pancreas, bile ducts, or intestines may also make it harder to absorb RELYVRIO
Salt (sodium) retention. RELYVRIO contains a high amount of salt. For people who are sensitive to salt intake, such as people with heart failure, high blood pressure, or kidney problems, limit the amount of salt you eat and drink. Talk to your doctor about the total amount of daily salt that is right for you. Your doctor will monitor you for signs and symptoms of salt retention during your treatment with RELYVRIO

The most common side effects of RELYVRIO include diarrhea, abdominal pain, nausea, and upper respiratory tract infection.

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of RELYVRIO. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch(opens new window) or call 1-800-FDA-1088.

INDICATION

RELYVRIO is indicated for the treatment of amyotrophic lateral sclerosis (ALS) in adults.

For additional information about RELYVRIO, please see the full Prescribing Information(opens a PDF document in a new window) and Medication Guide(opens a PDF document in a new window).