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Vladimir, living with ALS

Taking RELYVRIO

LET’S DO THIS

Start RELYVRIO® with the right information

Vladimir, living with ALS

Vladimir is a loving husband and father and a dedicated academic. From reading in Spanish to creating ever-challenging math games with his kids, he is always investing in the next generation. He also mentors college students, dreaming of developing the next leaders in the scientific workforce. With so much belief in the future of his kids and community, Vladimir isn’t giving up the fight against ALS.

WHAT TO EXPECT WHEN TAKING RELYVRIO

This useful information can help you start on your RELYVRIO treatment journey. It’s also important to know that ALS can affect people differently. An individual’s response to ALS treatments—including RELYVRIO—may vary. Your doctor will explain the benefits and side effects associated with taking RELYVRIO.

Slow disease progression

RELYVRIO IS NOT A CURE

While RELYVRIO will not stop ALS, it may help slow down disease progression.

Generally well-tolerated

WHAT TO KNOW ABOUT SIDE EFFECTS

The most common side effects for RELYVRIO include diarrhea, abdominal pain, nausea, and upper respiratory tract infection.

Managing the taste

MANAGING THE TASTE

The taste of RELYVRIO can vary from person to person. Talk to your doctor about managing the taste of RELYVRIO.

  • When mixed with water, RELYVRIO may have a fruity smell, but that may not reflect its actual taste
  • RELYVRIO may have a bitter aftertaste. In the clinical trial, participants were allowed to try to lessen or remove the bitter aftertaste by:
    • Using mint-flavored mouth strips or mouth spray immediately before or after taking RELYVRIO
    • Eating a small snack or honey after taking RELYVRIO
    • Drinking milk after taking RELYVRIO
    • Avoiding fruit juice immediately afterwards, as it can make the aftertaste worse
Take alone or with certain other ALS treatments

RELYVRIO AND OTHER TREATMENTS

If prescribed by your doctor, RELYVRIO can be taken alone or with certain other FDA-approved treatments for ALS. Before taking any additional medications, talk to your doctor.

Talk to your doctor

IF RELYVRIO SEEMS RIGHT FOR YOU

First, talk to your doctor to determine if RELYVRIO may serve as a part of you and your doctor’s plan to manage ALS.

Download the doctor discussion guide to help facilitate your conversation.

Doctor Discussion Guide

If you and your doctor decide that RELYVRIO is right for you, it’s important to work together to fill out the RELYVRIO Enrollment Form, which serves as your prescription for RELYVRIO. It may take some time between submitting the RELYVRIO Enrollment Form and getting RELYVRIO delivered to your home, so it’s important to reach out to your doctor and start the enrollment process as soon as possible.

Vladimir, living with ALS, hugging daughter

I’M NOT ALONE
IN MY JOURNEY

Personalized support and other helpful resources are available

Vladimir, living with ALS
Image
Amylyx Care Team (ACT)™ Support Program Logo

The Amylyx Care Team (ACT)™ Provides Support You Can Count On

The ACT Support Program is designed to help provide you with support as you start and continue on your RELYVRIO prescription that your doctor has prescribed.

If your doctor has decided that RELYVRIO is right for you, that’s when ACT comes in. ACT is a personalized support program designed to help meet your individual needs as you start and continue on RELYVRIO.

ACT team members are available to assist you Monday through Friday, 8:00 AM to 8:00 PM ET

IMPORTANT SAFETY INFORMATION

Before you receive RELYVRIO, tell your doctor about all of your medical conditions, including if you:

  • Have pancreas, liver, or intestinal problems
  • Have heart failure, including congestive heart failure
  • Have high blood pressure
  • Have kidney problems
  • Are pregnant or plan to become pregnant. It is not known if RELYVRIO will harm your unborn baby
  • Are breastfeeding or plan to breastfeed. It is not known if RELYVRIO passes into your breast milk. You and your doctor should decide the best way to feed your baby

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements and any taurursodiol products, such as tauroursodeoxycholic acid (TUDCA).

RELYVRIO may affect the way other medicines work, and other medicines may affect how RELYVRIO works.

What are the possible side effects of RELYVRIO?

RELYVRIO may cause serious side effects, including:

  • Changes in bile acid levels. RELYVRIO may increase bile acid levels and cause worsening diarrhea if you already have problems with your liver, bile ducts, or pancreas. Your doctor should monitor you for these side effects. Some disorders of the pancreas, bile ducts, or intestines may also make it harder to absorb RELYVRIO
  • Salt (sodium) retention. RELYVRIO contains a high amount of salt. For people who are sensitive to salt intake, such as people with heart failure, high blood pressure, or kidney problems, limit the amount of salt you eat and drink. Talk to your doctor about the total amount of daily salt that is right for you. Your doctor will monitor you for signs and symptoms of salt retention during your treatment with RELYVRIO

The most common side effects of RELYVRIO include diarrhea, abdominal pain, nausea, and upper respiratory tract infection.

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of RELYVRIO. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch(opens new window) or call 1-800-FDA-1088.

WHAT IS RELYVRIO?

RELYVRIO is a prescription medicine used to treat adults with amyotrophic lateral sclerosis (ALS).

For additional information, please see the Summary of Information About RELYVRIO(opens a PDF document in a new window).

IMPORTANT SAFETY INFORMATION

Before you receive RELYVRIO, tell your doctor about all of your medical conditions, including if you:

  • Have pancreas, liver, or intestinal problems
  • Have heart failure, including congestive heart failure
  • Have high blood pressure
  • Have kidney problems
  • Are pregnant or plan to become pregnant. It is not known if RELYVRIO will harm your unborn baby
  • Are breastfeeding or plan to breastfeed. It is not known if RELYVRIO passes into your breast milk. You and your doctor should decide the best way to feed your baby

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements and any taurursodiol products, such as tauroursodeoxycholic acid (TUDCA).

RELYVRIO may affect the way other medicines work, and other medicines may affect how RELYVRIO works.

What are the possible side effects of RELYVRIO?

RELYVRIO may cause serious side effects, including:

  • Changes in bile acid levels. RELYVRIO may increase bile acid levels and cause worsening diarrhea if you already have problems with your liver, bile ducts, or pancreas. Your doctor should monitor you for these side effects. Some disorders of the pancreas, bile ducts, or intestines may also make it harder to absorb RELYVRIO
  • Salt (sodium) retention. RELYVRIO contains a high amount of salt. For people who are sensitive to salt intake, such as people with heart failure, high blood pressure, or kidney problems, limit the amount of salt you eat and drink. Talk to your doctor about the total amount of daily salt that is right for you. Your doctor will monitor you for signs and symptoms of salt retention during your treatment with RELYVRIO

The most common side effects of RELYVRIO include diarrhea, abdominal pain, nausea, and upper respiratory tract infection.

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of RELYVRIO. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch(opens new window) or call 1-800-FDA-1088.

WHAT IS RELYVRIO?

RELYVRIO is a prescription medicine used to treat adults with amyotrophic lateral sclerosis (ALS).

For additional information, please see the Summary of Information About RELYVRIO(opens a PDF document in a new window).